Immune-mediated nephropathy

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Immunologic nephropathies are a group of chronic glomerular diseases with the same immunopathologic features caused by multiple etiologies. Immunologic nephropathies include purpura nephritis, lupus nephritis, and IgA nephropathy. If renal insufficiency, proteinuria more than 1.5g/d, hypertension, glomerulosclerosis, and interstitial fibrosis occur after the disease, about 35% of them eventually develop uremia. We have established a stable model of multiple immune nephropathies, which is suitable for the study of drugs for preclinical immune nephropathies and the evaluation of new drugs. If you have a project need and experience more of our professional services, please contact us.

Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
Immune-mediated nephropathy	Model of passive Hyman's nephritis induced by renal brush border antibody (Fx1A)		√
	MRLMpJ-Faslpr mouse model of systemic lupus erythematosus	√
	IgA nephropathy model	√	√