Hypothyroidism

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Hypothyroidism, commonly known as hypothyroidism, is a generalized low metabolic syndrome caused by a variety of reasons that result in decreased production or action of thyroid hormones. Hypothyroidism is highly prevalent in people with autoimmune diseases, congenital thyroid disorders, and radiation exposure. Depending on where the lesion occurs, hypothyroidism can be categorized into primary, central, and thyroid hormone resistance syndromes. Common clinical symptoms include chills, fatigue, decreased cellular metabolic rate, and slow heartbeat. Symptoms lack specificity and occur more often in the elderly, and are often misdiagnosed as anemia or depression. Untreated hypothyroidism can lead to a variety of complications, such as heart failure, depression, peripheral neuropathy, infertility, etc., which can be life-threatening. We have established a stable model of hypothyroidism caused by different triggers, which is suitable for the research of preclinical treatment of hypothyroidism and evaluation of new drugs. If you have a project need and experience more of our professional services, please contact us.

Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
Hypothyroidism	Thyroidectomy-induced hypothyroidism model in SD rats		√