Dermatomyositis

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Dermatomyositis

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  • Dermatomyositis is an autoimmune disease characterized by distinctive skin damage and muscle weakness. Based on clinical manifestations and pathologic features, dermatomyositis can be divided into several types, the most common of which are adult dermatomyositis (ADM) and pediatric dermatomyositis (JDM). Currently, its treatment is based on glucocorticoid or glucocorticoid combined with immunosuppressive therapy. Some patients who are ineffective on both hormones and immunosuppressants may undergo plasma exchange. If the disease is not treated or controlled in time, it may lead to serious complications and even death. Preventive methods include strengthening personal hygiene, preventing infection, and paying attention to sun protection. We have established a stable model of dermatomyositis, which is suitable for the study of drugs for preclinical dermatomyositis and the evaluation of new drugs. If you have a project need and experience more of our professional services, please contact us.
Disease NameModel nameSpecies of animals
MouseRatHamsterGuinea pigFerretRabbitCatDogPigNon-human primate
DermatomyositisSepticemia model of cecal filtrate infection
Model of septicemia induced by ligation of a threaded cecum
A model of LPS-induced sepsis

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