Acute liver injury

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Acute liver injury is mostly secondary to drug-induced hepatitis or hemorrhagic shock after trauma, resulting in injury secondary to insufficient blood supply and perfusion to the liver, and the patient will also have obvious pain in the liver area, as well as abdominal distension and jaundice, which will be manifested as an increase in aminotransferases and bilirubin. Acute phase should be treated systematically, otherwise liver insufficiency or even liver failure may occur, and in severe cases, liver necrosis may occur, which is life-threatening. We have established a stable carbon tetrachloride-induced acute liver injury model and an acetaminophen (APAP)-induced acute liver injury model, which are suitable for the study of drugs for preclinical NASH and the evaluation of new drugs. If you have a project need and experience more of our professional services, please contact us.

Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
Acute liver injury	Carbon tetrachloride-induced acute liver injury model	√	√								√
	DDC-induced acute liver injury	√
	Acetaminophen (APAP)-induced acute liver injury model	√