Acute kidney injury

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Acute kidney injury (AKI) is a group of clinical syndromes characterized by a sudden (within 1-7 d) and sustained (>24 h) decline in renal function, defined as a rise in serum creatinine (SCr) of at least 0.5 mg/dl 1 , manifested by azotemia, water-electrolyte and acid-base balance, and generalized systemic symptoms, which may be associated with oliguria (<400 ml/24h or 17 ml/h) or anuria (<100 ml/24h). /24h). We have established stable multiple models of acute kidney injury, which are suitable for preclinical studies of drugs with acute kidney injury and evaluation of new drugs. If you have project needs and experience more of our professional services, please contact us.

Disease Name	Model name	Species of animals
Disease Name	Model name	Mouse	Rat	Hamster	Guinea pig	Ferret	Rabbit	Cat	Dog	Pig	Non-human primate
Acute kidney injury	Ischemia-reperfusion-induced acute kidney injury model	√	√				√				√
	Cisplatin-induced acute kidney injury model	√	√
	Glycerol-induced acute renal failure model		√